Azo compounds
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Filtered Search Results
eMolecules EMOLECULES INC
5000482578 2 2-AZOBIS 2-2-IMIDAZOLI 25G
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Apexbio Technology LLC KW 2449 1000669-72-6 10mg
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KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
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Cambridge Isotope Laboratories 2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL
2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL
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eMolecules EMOLECULES INC
5000488868 1 1-AZOBISN N-DIMETHYLFOR 1G
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Apexbio Technology LLC KW 2449 1000669-72-6 10mM (in 1mL DMSO)
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 2 2-AZOBIS 2-2-IMIDAZOL 100G
5000224519 2 2-AZOBIS 2-2-IMIDAZOL 100G
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eMolecules 2 2-AZOBIS 2-METHYL-N-2-H 5G
5000164563 2 2-AZOBIS 2-METHYL-N-2-H 5G
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eMolecules EMOLECULES INC
5000488181 DIAMIDE 25G
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Medchemexpress LLC {4-[(E)-2-(1H-indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol⁻¹ | C20H20N4O | 1 ML
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KW-2449 is a multi-targeted small-molecule kinase inhibitor active against FLT3, ABL (including ABL T315I), and Aurora kinases. It exhibits low-nanomolar potency and is supplied for laboratory research use.
- Multi-targeted kinase inhibitor effective against FLT3, ABL, and Aurora kinases.
- Low-nanomolar potency with reported IC50s of 6.6, 14, 4, and 48 nM (FLT3, ABL, ABL T315I, Aurora).
- Provided as a 10 mM solution in DMSO (1 mL) or as a solid in multiple milligram sizes.
- High purity suitable for research (reported purity 99.9%).
- Molecular formula C20H20N4O; molecular weight 332.40 g·mol⁻¹.
- For research use only; not for human or veterinary use.
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eMolecules EMOLECULES INC
NC3929429 2 2-AZOBIS 2-METHYLPROPIONITR
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Medchemexpress LLC [4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol-1 | C20H20N4O | 100 MG
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KW-2449 is a small-molecule, multi-targeted kinase inhibitor used in research to study signaling pathways and leukemia models. Supplied as a high-purity white powder, it is characterized by the molecular formula C20H20N4O and a molecular weight of 332.40 g·mol-1.
- Multi-targeted kinase inhibition: inhibits FLT3, ABL, ABL T315I, and Aurora kinases at low nanomolar IC50s.
- High purity: reported 99.91% purity suitable for biochemical and cell-based assays.
- Solid powder form: convenient for dissolution in common organic solvents and buffers.
- Well-characterized: SMILES and molecular properties available for computational and analytical use.
- For research use only: not intended for human or clinical use.
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Chem-Impex International, Inc. 3-Azidopropylamine | MFCD11046568 | 1G
3-Azidopropylamine , Purity: 98% , Mol Wt: 100.12 , 88192-19-2 , MFCD11046568 , 1 g
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Spectrum Chemical Manufacturing Corporation Peanut Oil, NF, Spectrum™ Chemical
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CAS: 8002-03-7
| CAS | 8002-03-7 |
|---|
1,1'-Azobis(N,N-dimethylformamide), 98%, Thermo Scientific™
CAS: 10465-78-8 Molecular Formula: C6H12N4O2 Molecular Weight (g/mol): 172.188 InChI Key: VLSDXINSOMDCBK-BQYQJAHWSA-N Synonym: diamide,n,n,n',n'-tetramethylazodicarboxamide,tmad,1,1'-azobis n,n-dimethylformamide,tetramethyldiazenedicarboxamide,diazenedicarboxamide, tetramethyl,n,n,n',n'-tetramethylazoformamide,diazenedicarboxylic acid bis n,n-dimethylamide,n,n,n',n'-tetramethylazobisformamide,tetramethylazodicarboxamide PubChem CID: 5353800 ChEBI: CHEBI:48963 IUPAC Name: (3E)-3-(dimethylcarbamoylimino)-1,1-dimethylurea SMILES: CN(C)C(=O)N=NC(=O)N(C)C
| PubChem CID | 5353800 |
|---|---|
| CAS | 10465-78-8 |
| Molecular Weight (g/mol) | 172.188 |
| ChEBI | CHEBI:48963 |
| SMILES | CN(C)C(=O)N=NC(=O)N(C)C |
| Synonym | diamide,n,n,n',n'-tetramethylazodicarboxamide,tmad,1,1'-azobis n,n-dimethylformamide,tetramethyldiazenedicarboxamide,diazenedicarboxamide, tetramethyl,n,n,n',n'-tetramethylazoformamide,diazenedicarboxylic acid bis n,n-dimethylamide,n,n,n',n'-tetramethylazobisformamide,tetramethylazodicarboxamide |
| IUPAC Name | (3E)-3-(dimethylcarbamoylimino)-1,1-dimethylurea |
| InChI Key | VLSDXINSOMDCBK-BQYQJAHWSA-N |
| Molecular Formula | C6H12N4O2 |